Title : Novel 4-(aryloxy)tetrahydropyridine analogs of MPTP as monoamine oxidase A and B substrates.

Pub. Date : 1994 Apr 1

PMID : 8151621






1 Functional Relationships(s)
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1 The expected dihydropyridinium metabolites generated from these MAO-A- and MAO-B-catalyzed oxidations of the 4-(aryloxy)tetrahydropyridine analogs were found to undergo rapid hydrolytic cleavage to yield the corresponding arenol and 1-methyl-2,3-dihydro-4-pyridone, a species that could be monitored spectrophotometrically. 1-methyl-2,3-dihydro-4-pyridone monoamine oxidase B Homo sapiens