Title : Effect of chronic treatment with the antidepressant tianeptine on the hypothalamo-pituitary-adrenal axis.

Pub. Date : 1994 Jan 14

PMID : 8149980






1 Functional Relationships(s)
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1 In contrast, chronic administration of tianeptine (10 mg/kg twice a day for 15 days) induced a significant decrease in the concentration of corticotropin-releasing factor (CRF) in the hypothalamus and adrenocorticotropin (ACTH) in the anterior lobe of the pituitary. tianeptine corticotropin releasing hormone Rattus norvegicus