Title : Neuropeptide-Y potentiates the secretion of vasopressin from the neurointermediate lobe of the rat pituitary gland.

Pub. Date : 1994 Apr

PMID : 8137725






2 Functional Relationships(s)
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1 To investigate the possibility that NPY exerts a modulatory role on the release of neurohypophysial hormones, we have studied the actions of NPY on potassium-evoked release of vasopressin and oxytocin from the rat neurointermediate lobe in vitro. Potassium arginine vasopressin Rattus norvegicus
2 NPY dose-dependently potentiated vasopressin release evoked by high extracellular potassium (56 mM), with a maximal enhancement of 223% (10(-7) M NPY). Potassium arginine vasopressin Rattus norvegicus