Title : Lysophosphatidylcholine in oxidized low-density lipoprotein increases endothelial susceptibility to polymorphonuclear leukocyte-induced endothelial dysfunction in porcine coronary arteries. Role of protein kinase C.

Pub. Date : 1994 Apr

PMID : 8137494






1 Functional Relationships(s)
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1 Treatment of the arteries with phorbol 12-myristate 13-acetate, a potent stimulator of PKC, induced ICAM-1 expression and enhanced the endothelial adhesiveness to PMNs and PMN-induced EDR impairment, mimicking the effects of Ox-LDL. Tetradecanoylphorbol Acetate intercellular adhesion molecule 1 Homo sapiens