Title : Neutrophil-activating peptides NAP-2 and IL-8 bind to the same sites on neutrophils but interact in different ways. Discrepancies in binding affinities, receptor densities, and biologic effects.

Pub. Date : 1994 Mar 1

PMID : 8133058






1 Functional Relationships(s)
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1 We observed complete cross-competition of unlabeled IL-8 with 125I-labeled-NAP-2 and of unlabeled NAP-2 with 125I-labeled IL-8, indicating the absence of monospecific binding sites for either chemokine. Iodine-125 C-X-C motif chemokine ligand 8 Homo sapiens