Title : An IL-4 receptor region containing an insulin receptor motif is important for IL-4-mediated IRS-1 phosphorylation and cell growth.

Pub. Date : 1994 Mar 11

PMID : 8124718






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Interleukin-4 (IL-4) treatment of 32D cells overexpressing insulin receptor substrate 1 (IRS-1) causes prompt tyrosine phosphorylation of IRS-1. Tyrosine interleukin 4 Mus musculus
2 Interleukin-4 (IL-4) treatment of 32D cells overexpressing insulin receptor substrate 1 (IRS-1) causes prompt tyrosine phosphorylation of IRS-1. Tyrosine interleukin 4 Mus musculus
3 Thus, the central tyrosine of the I4R motif has a major role in IL-4-mediated signal transduction in 32D cells. Tyrosine interleukin 4 Mus musculus