Title : Interleukin-1-mediated release of interleukin-8 by asbestos-stimulated human pleural mesothelial cells.

Pub. Date : 1994 Mar

PMID : 8117443






2 Functional Relationships(s)
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1 Suspensions of amosite, chrysotile, or crocidolite asbestos in concentrations as low as 5 micrograms/ml enhanced release of IL-8 from HPMC during 6 h of incubation at 37 degrees C. Electron microscopy of asbestos-treated HPMC showed that the cells avidly engulfed each of the different types of asbestos fibers. Asbestos, Crocidolite C-X-C motif chemokine ligand 8 Homo sapiens
2 Preincubation of HPMC with IL-1 receptor antagonist (IL-1ra) significantly decreased release of IL-8 after stimulation with amosite or crocidolite asbestos. Asbestos, Crocidolite C-X-C motif chemokine ligand 8 Homo sapiens