Title : Synthesis and beta-adrenergic antagonist activity of heterocyclic propanolamines.

Pub. Date : 1993 Jun

PMID : 8104518






1 Functional Relationships(s)
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Protein Name
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1 beta 1-Adrenolytic (atria) structure-activity correlations indicated that replacement of the 1-naphthyl moiety of propranolol by a 4-quinolyl- (10), 2-quinolyl- (24), or 2-pyrimidyl- (26) heterocyclic moiety resulted in a 10-16 fold reduction in activity. Propranolol potassium calcium-activated channel subfamily M regulatory beta subunit 1 Homo sapiens