Title : Vagal afferent pathway mediates physiological action of cholecystokinin on pancreatic enzyme secretion.

Pub. Date : 1993 Jul

PMID : 8100836






2 Functional Relationships(s)
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1 Pretreatment with atropine or hexamethonium completely abolished pancreatic protein response to low doses of CCK-8 (10-40 pmol/kg per h) but had only partial effect on doses > 40 pmol/kg per h. Bilateral vagotomy also abolished the pancreatic responses to low doses of CCK-8. Hexamethonium cholecystokinin Rattus norvegicus
2 Pretreatment with atropine or hexamethonium completely abolished pancreatic protein response to low doses of CCK-8 (10-40 pmol/kg per h) but had only partial effect on doses > 40 pmol/kg per h. Bilateral vagotomy also abolished the pancreatic responses to low doses of CCK-8. Hexamethonium cholecystokinin Rattus norvegicus