Title : Fragments of human fibroblast collagenase: interaction with metalloproteinase inhibitors and substrates.

Pub. Date : 1994 Sep 21

PMID : 8086430






1 Functional Relationships(s)
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1 Complex formation with the whole molecule is prevented by EDTA and by 1,10-phenanthroline demonstrating the importance of the active site; additionally TIMP and TIMP-2 will compete with a reversibly bound peptide hydroxamic acid inhibitor for the active site. 1,10-phenanthroline TIMP metallopeptidase inhibitor 2 Homo sapiens