Title : Influenza B virus neuraminidase can synthesize its own inhibitor.

Pub. Date : 1993 Sep 15

PMID : 8069621






1 Functional Relationships(s)
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1 RESULTS: We have determined the crystal structure at 1.8 A resolution of two complexes of influenza B/Beijing neuraminidase containing either the reaction product, sialic acid, or the transition state analogue inhibitor, 2,3-dehydro-2-deoxy-N-acetylneuraminic acid (DANA). 2-deoxy-2,3-dehydro-N-acetylneuraminic acid neuraminidase 1 Homo sapiens