Title : Platelet secretory phospholipase A2 fails to induce rabbit platelet activation and to release arachidonic acid in contrast with venom phospholipases A2.

Pub. Date : 1994 Aug 25

PMID : 8068732






2 Functional Relationships(s)
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1 Interestingly, PLA2 able to induce platelet activation efficiently hydrolyse phosphatidylcholine, while those inactive on platelets did not. Phosphatidylcholines phospholipase A2 group IIA Homo sapiens
2 Moreover, the ability of PLA2 to induce platelet activation is not related to its structural group (I, II, III) but rather to its origin (venom vs. mammalian) and capacity to hydrolyse phosphatidylcholine, the major phospholipid of the outer leaflet of the plasma membrane. Phosphatidylcholines phospholipase A2 group IIA Homo sapiens