Title : Stabilization of the mRNA for the uncoupling protein thermogenin by transcriptional/translational blockade and by noradrenaline in brown adipocytes differentiated in culture: a degradation factor induced by cessation of stimulation?

Pub. Date : 1994 Aug 15

PMID : 8068027






3 Functional Relationships(s)
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1 Stabilization of the mRNA for the uncoupling protein thermogenin by transcriptional/translational blockade and by noradrenaline in brown adipocytes differentiated in culture: a degradation factor induced by cessation of stimulation? Norepinephrine uncoupling protein 1 (mitochondrial, proton carrier) Mus musculus
2 After 7 days in culture, the cells were stimulated for 24 h with noradrenaline, and a high level of thermogenin mRNA was then observed. Norepinephrine uncoupling protein 1 (mitochondrial, proton carrier) Mus musculus
3 The presence of noradrenaline during transcriptional blockade led to a further stabilization of thermogenin mRNA. Norepinephrine uncoupling protein 1 (mitochondrial, proton carrier) Mus musculus