Title : Granulocyte-macrophage colony-stimulating factor expression is regulated at transcriptional and posttranscriptional levels in a murine bone marrow stromal cell line.

Pub. Date : 1994 Aug

PMID : 8062890






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Addition to stromal cells of the soluble cAMP agonist 8-bromo-cAMP (8BrcAMP) at 0.5 to 1 mM stimulated IL-6 mRNA expression acting alone, and it was additive with IL-1 or IL-1 plus TNF-alpha in stimulating IL-6 expression. 8-Bromo Cyclic Adenosine Monophosphate tumor necrosis factor Mus musculus
2 Addition to stromal cells of the soluble cAMP agonist 8-bromo-cAMP (8BrcAMP) at 0.5 to 1 mM stimulated IL-6 mRNA expression acting alone, and it was additive with IL-1 or IL-1 plus TNF-alpha in stimulating IL-6 expression. 8-Bromo Cyclic Adenosine Monophosphate tumor necrosis factor Mus musculus
3 On the other hand, 8BrcAMP inhibited GM-CSF mRNA expression stimulated by IL-1 or IL-1 plus TNF-alpha. 8-Bromo Cyclic Adenosine Monophosphate tumor necrosis factor Mus musculus