Pub. Date : 1975 Jun
PMID : 806079
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Nature of the increase in renal ornithine decarboxylase activity after cycloheximide administration in the rat. | Cycloheximide | ornithine decarboxylase 1 | Rattus norvegicus |
| 2 | The present study was designed to determine whether the increase in rat renal ornithine decarboxylase (L-ornithine carboxy-lyase, EC 4.1.1.17) activity after cycloheximide administration was a primary effect on the kidney or was a secondary effect of adrenal or pituitary hormones released in response to the drug. | Cycloheximide | ornithine decarboxylase 1 | Rattus norvegicus |
| 3 | Renal ornithine decarboxylase activity was reduced approximately 70% 1 hr after intraperitoneal administration of doses of cycloheximide that also inhibited renal protein synthesis by 68-95% within 1 hr. | Cycloheximide | ornithine decarboxylase 1 | Rattus norvegicus |
| 4 | Peak ornithine decarboxylase activity was directly proportional to cycloheximide doses up to 250 mug; larger doses, which almost abolished protein synthesis for 8 hr, where inhibitory. | Cycloheximide | ornithine decarboxylase 1 | Rattus norvegicus |