Title : Comparison of the low energy conformations of an oncogenic and a non-oncogenic p21 protein, neither of which binds GTP or GDP.

Pub. Date : 1994 Feb

PMID : 8060496






4 Functional Relationships(s)
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1 Comparison of the low energy conformations of an oncogenic and a non-oncogenic p21 protein, neither of which binds GTP or GDP. Guanosine Triphosphate H3 histone pseudogene 16 Homo sapiens
2 Since p21 is normally activated by the binding of GTP in place of GDP, it has been postulated that oncogenic forms must retain bound GTP for prolonged time periods. Guanosine Triphosphate H3 histone pseudogene 16 Homo sapiens
3 Since p21 is normally activated by the binding of GTP in place of GDP, it has been postulated that oncogenic forms must retain bound GTP for prolonged time periods. Guanosine Triphosphate H3 histone pseudogene 16 Homo sapiens
4 However, two multiply substituted p21 proteins have been cloned, neither of which binds GDP or GTP. Guanosine Triphosphate H3 histone pseudogene 16 Homo sapiens