Title : Demonstration of a functionally active tPA-like plasminogen activator in human platelets.

Pub. Date : 1994 Apr

PMID : 8052969






3 Functional Relationships(s)
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1 Fibrin zymographic analysis of affinity-purified tPA-like-PA demonstrated a major and a minor fibrin lysis zone, which approximately corresponded to the tPA-like-PA and its complex with PAI-1 observed by Western blots. Protactinium serpin family E member 1 Homo sapiens
2 Fibrin zymographic analysis of affinity-purified tPA-like-PA demonstrated a major and a minor fibrin lysis zone, which approximately corresponded to the tPA-like-PA and its complex with PAI-1 observed by Western blots. Protactinium serpin family E member 1 Homo sapiens
3 We conclude that platelets contain a functionally active tPA-like-PA, whose low fibrinolytic activity might be due to its readily forming a complex with PAI-1. Protactinium serpin family E member 1 Homo sapiens