Pub. Date : 1994 Jun
PMID : 8043498
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | This aberrant response was due to a threonine to alanine substitution at amino acid position 868 in the steroid binding domain of the androgen receptor (AR). | Steroids | androgen receptor | Homo sapiens |
| 2 | This aberrant response was due to a threonine to alanine substitution at amino acid position 868 in the steroid binding domain of the androgen receptor (AR). | Steroids | androgen receptor | Homo sapiens |
| 3 | Therefore, in LNCaP cells the mutation in the steroid binding domain of the AR prevents a blockade of receptor function by most antiandrogens, but not by ICI 176,334, probably because of a different mechanism by which this compound blocks receptor function. | Steroids | androgen receptor | Homo sapiens |