Title : Effects of ammonium on intracellular pH in rat medullary thick ascending limb: mechanisms of apical membrane NH4+ transport.

Pub. Date : 1994 May

PMID : 8035168






2 Functional Relationships(s)
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1 Luminal furosemide (10(-4) M) reduced the initial rate of cell acidification by 70% and the fall in steady state pHi by 35%. Furosemide glucose-6-phosphate isomerase Rattus norvegicus
2 Addition of furosemide to the lumen abolished net ammonium absorption and caused pHi to increase abruptly (dpHi/dt = 0.8 U/min) to 7.0. Furosemide glucose-6-phosphate isomerase Rattus norvegicus