Title : Cyclosporin A sensitivity of the NF-kappa B site of the IL2R alpha promoter in untransformed murine T cells.

Pub. Date : 1994 Jun 11

PMID : 8029023






4 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Cyclosporin A sensitivity of the NF-kappa B site of the IL2R alpha promoter in untransformed murine T cells. Cyclosporine nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus
2 Based on these results, we propose that the NF-kappa B site of the IL2R alpha promoter mediates at least part of the CsA sensitivity of IL2R alpha gene induction in untransformed T cells, possibly because de novo synthesis of p105 NF-kappa B is required for sustained IL2R alpha expression. Cyclosporine nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus
3 Based on these results, we propose that the NF-kappa B site of the IL2R alpha promoter mediates at least part of the CsA sensitivity of IL2R alpha gene induction in untransformed T cells, possibly because de novo synthesis of p105 NF-kappa B is required for sustained IL2R alpha expression. Cyclosporine nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus
4 Based on these results, we propose that the NF-kappa B site of the IL2R alpha promoter mediates at least part of the CsA sensitivity of IL2R alpha gene induction in untransformed T cells, possibly because de novo synthesis of p105 NF-kappa B is required for sustained IL2R alpha expression. Cyclosporine nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus