Title : Inhibition by nickel of endothelin-1-induced tension and associated 45Ca movements in rabbit aorta.

Pub. Date : 1994 Dec

PMID : 7996430






2 Functional Relationships(s)
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1 Contractions induced by 10 nM endothelin-1 (ET) in the rabbit aortic media intimal layer were inhibited by prior exposure to 100 microM Ni++ (33.1%) or to a Ca(++)-free buffer (80.2%) but were unaffected by pretreatment with 0.1 microM nifedipine. Nifedipine endothelin-1 Oryctolagus cuniculus
2 Contractions induced by 10 nM endothelin-1 (ET) in the rabbit aortic media intimal layer were inhibited by prior exposure to 100 microM Ni++ (33.1%) or to a Ca(++)-free buffer (80.2%) but were unaffected by pretreatment with 0.1 microM nifedipine. Nifedipine endothelin-1 Oryctolagus cuniculus