Title : The cyclic adenosine 3',5'-monophosphate- and the glucocorticoid-dependent enhancers are targets for insulin repression of tyrosine aminotransferase gene transcription.

Pub. Date : 1994 Jul

PMID : 7984151






3 Functional Relationships(s)
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1 The cyclic adenosine 3",5"-monophosphate- and the glucocorticoid-dependent enhancers are targets for insulin repression of tyrosine aminotransferase gene transcription. Cyclic AMP insulin Homo sapiens
2 Here, we show that both the cAMP- and glucocorticoid-inducible enhancers are targets for the antagonistic effects of insulin. Cyclic AMP insulin Homo sapiens
3 The insulin-responsive sequences coincide with the CREB-binding site of the cAMP-responsive enhancer and a hepatocyte nuclear factor-3-binding site within the glucocorticoid-responsive unit. Cyclic AMP insulin Homo sapiens