Title : Effects of lovastatin on ApoA- and ApoB-containing lipoproteins. Families in a subpopulation of patients participating in the Monitored Atherosclerosis Regression Study (MARS).

Pub. Date : 1994 Dec

PMID : 7981178






2 Functional Relationships(s)
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1 Effects of lovastatin on ApoA- and ApoB-containing lipoproteins. Lovastatin apolipoprotein B Homo sapiens
2 To establish whether lovastatin, an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, exhibits a specific effect on apolipoprotein (apo) A- and apoB-containing lipoproteins, 63 subjects, a subset of the 270 Monitored Atherosclerosis Regression Study (MARS) patients with hypercholesterolemia (190 to 295 mg/dL) and documented coronary artery disease, were randomized into either lovastatin 40 mg twice daily or matching placebo tablets twice daily. Lovastatin apolipoprotein B Homo sapiens