Title : Selectivity of isoprenoid-containing imidazole antifungal compounds for sterol 14-demethylase P450 (P450(14)DM) and 7-ethoxycoumarin O-deethylase P450 of rat liver microsomes.

Pub. Date : 1994 Oct 18

PMID : 7980623






2 Functional Relationships(s)
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1 These results suggest that azole compounds interacting with the side-chain recognition site of P450(14)DM may be good candidates as antifungal agents selective for fungal P450(14)DM. Azoles cytochrome P450, family 51 Rattus norvegicus
2 These results suggest that azole compounds interacting with the side-chain recognition site of P450(14)DM may be good candidates as antifungal agents selective for fungal P450(14)DM. Azoles cytochrome P450, family 51 Rattus norvegicus