Title : Differential inhibition of human prostaglandin endoperoxide H synthases-1 and -2 by nonsteroidal anti-inflammatory drugs.

Pub. Date : 1994 Nov

PMID : 7965814






2 Functional Relationships(s)
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1 For cells pretreated with flurbiprofen or meclofenamate, hPGHS-2 activities, but not hPGHS-1 activities, were recovered relatively rapidly; with indomethacin, recoveries of hPGHS-1 and hPGHS-2 activities were both slow. Flurbiprofen prostaglandin-endoperoxide synthase 2 Homo sapiens
2 For cells pretreated with flurbiprofen or meclofenamate, hPGHS-2 activities, but not hPGHS-1 activities, were recovered relatively rapidly; with indomethacin, recoveries of hPGHS-1 and hPGHS-2 activities were both slow. Flurbiprofen prostaglandin-endoperoxide synthase 2 Homo sapiens