Title : Cloning and identification of annexin II as an autocrine/paracrine factor that increases osteoclast formation and bone resorption.

Pub. Date : 1994 Nov 18

PMID : 7961821






3 Functional Relationships(s)
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Protein Name
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1 Purified recombinant AXII significantly increased MNC formation in human bone marrow cultures in the absence of 1,25-(OH)2 vitamin D3 and enhanced MNC formation in mouse bone marrow cultures treated with 10(-9) M 1,25-(OH)2 vitamin D3. Calcitriol annexin A2 Homo sapiens
2 Purified recombinant AXII significantly increased MNC formation in human bone marrow cultures in the absence of 1,25-(OH)2 vitamin D3 and enhanced MNC formation in mouse bone marrow cultures treated with 10(-9) M 1,25-(OH)2 vitamin D3. Calcitriol annexin A2 Homo sapiens
3 Treatment of fetal rat long bones with AXII and 1,25-(OH)2 vitamin D3 significantly increased bone resorption compared to 1,25-(OH)2 vitamin D3 alone. Calcitriol annexin A2 Homo sapiens