Pub. Date : 1994 Dec 1
PMID : 7954469
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Involvement of human glutathione S-transferase isoenzymes in the conjugation of cyclophosphamide metabolites with glutathione. | Cyclophosphamide | glutathione S-transferase kappa 1 | Homo sapiens |
| 2 | However, little is known about the GSH-/GST-dependent biotransformation of alkylating agents, including cyclophosphamide. | Cyclophosphamide | glutathione S-transferase kappa 1 | Homo sapiens |
| 3 | Since all of the human GSTs tested did catalyze the formation of 4-GSCP, the role of 4-GSCP either as a transport form of activated cyclophosphamide or as a detoxification product is discussed. | Cyclophosphamide | glutathione S-transferase kappa 1 | Homo sapiens |