Title : Involvement of CYP2D6, CYP3A4, and other cytochrome P-450 isozymes in N-dealkylation reactions.

Pub. Date : 1994 Aug

PMID : 7949373






1 Functional Relationships(s)
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1 Metabolic N-dealkylation is a commonly observed biotransformation with tertiary and secondary amine drugs and related N-alkylated amides, but surprisingly little is known about the cytochrome P-450 isozymes involved in these dealkylation reactions. Nitrogen cytochrome P450 family 4 subfamily F member 3 Homo sapiens