Title : Stabilization of L-asparaginase modified with comb-shaped poly(ethylene glycol) derivatives, in vivo and in vitro.

Pub. Date : 1994 Jul-Aug

PMID : 7948093






1 Functional Relationships(s)
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1 L-Asparaginase from Escherichia coli was coupled with two types of comb-shaped copolymer of poly-(ethylene glycol) derivative and maleic anhydride (activated PM), having molecular weights of 13,000 and 100,000 (activated PM13 and PM100, respectively) with multivalent reaction sites. copolymer asparaginase and isoaspartyl peptidase 1 Rattus norvegicus