Title : Synthesis and antiproliferative activity of tyrphostins containing heteroaromatic moieties.

Pub. Date : 1994 Aug

PMID : 7916898






1 Functional Relationships(s)
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1 We have confirmed and extended the observation that the tyrphostins displayed an enhancement in their ability to inhibit the epidermal growth factor (EGF) receptor tyrosine kinase domain as the number of hydroxyl groups on the aromatic portion was increased. Tyrphostins epidermal growth factor receptor Homo sapiens