Pub. Date : 1994 Aug
PMID : 7915087
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Spontaneous and all-trans-retinoic acid (RA)-induced differentiation of normal human monocytes and of leukemic THP-1 monocytes into macrophages resulted in a progressive loss of adenosine 3",5"-cyclic monophosphate production induced by histamine via typical H2 receptors (H2R). | Tretinoin | GLI family zinc finger 2 | Homo sapiens |
| 2 | Spontaneous and all-trans-retinoic acid (RA)-induced differentiation of normal human monocytes and of leukemic THP-1 monocytes into macrophages resulted in a progressive loss of adenosine 3",5"-cyclic monophosphate production induced by histamine via typical H2 receptors (H2R). | Tretinoin | GLI family zinc finger 2 | Homo sapiens |
| 3 | In THP-1 cells and in HL-60 human acute myelocytic leukemia cells, RA treatment increased the abundance of the 4.5-kb messenger RNA of the H2R gene fourfold, suggesting transcriptional control by a RA response element. | Tretinoin | GLI family zinc finger 2 | Homo sapiens |