Title : Endogenous tumor necrosis factor functions as a resistant factor against adriamycin.

Pub. Date : 1994 Aug 1

PMID : 7914182






2 Functional Relationships(s)
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1 The stable transformants became resistant to adriamycin with increased levels of MnSOD. Doxorubicin superoxide dismutase 2 Homo sapiens
2 These results indicate that enTNF exerts its intracellular protective effect against adriamycin-induced cytotoxicity by the same mechanism as that against exogenous TNF and heat, namely scavenging reactive oxygen with induced MnSOD. Doxorubicin superoxide dismutase 2 Homo sapiens