Title : Taxol: mechanisms of action and resistance.

Pub. Date : 1993

PMID : 7912530






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 In human tumors resistant to Taxol, P-glycoprotein could be responsible for maintaining the drug below cytotoxic levels. Paclitaxel ATP binding cassette subfamily B member 1 Homo sapiens
2 Analyses of the MDR promoters that are involved in P-glycoprotein expression and overproduction revealed an interesting recombination event in a Taxol-resistant cell line. Paclitaxel ATP binding cassette subfamily B member 1 Homo sapiens