Pub. Date : 1994 Apr
PMID : 7907998
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Regulation of human insulin gene transcription by glucose, epinephrine, and somatostatin. | Epinephrine | insulin | Homo sapiens |
| 2 | Epinephrine significantly inhibited insulin-CAT reporter gene expression (61 +/- 5% of control), an effect mediated specifically by the human insulin gene promoter/enhancer sequence. | Epinephrine | insulin | Homo sapiens |
| 3 | Epinephrine significantly inhibited insulin-CAT reporter gene expression (61 +/- 5% of control), an effect mediated specifically by the human insulin gene promoter/enhancer sequence. | Epinephrine | insulin | Homo sapiens |
| 4 | Both epinephrine and somatostatin inhibited expression of the human insulin-CAT reporter gene in a concentration-dependent manner that paralleled inhibition of insulin secretion. | Epinephrine | insulin | Homo sapiens |
| 5 | Both epinephrine and somatostatin inhibited expression of the human insulin-CAT reporter gene in a concentration-dependent manner that paralleled inhibition of insulin secretion. | Epinephrine | insulin | Homo sapiens |
| 6 | These studies indicate that epinephrine and somatostatin lower HIT cell insulin mRNA levels in part by inhibiting insulin gene transcription. | Epinephrine | insulin | Homo sapiens |
| 7 | These studies indicate that epinephrine and somatostatin lower HIT cell insulin mRNA levels in part by inhibiting insulin gene transcription. | Epinephrine | insulin | Homo sapiens |