Title : Serotonergic inhibition of light-induced fos protein expression and extracellular glutamate in the suprachiasmatic nuclei.

Pub. Date : 1993 Sep 10

PMID : 7902183






3 Functional Relationships(s)
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1 injection of the serotonergic, quipazine, caused a marked decrease in the number of SCN cells expressing Fos protein-like immunoreactivity (Fos-LI) induced by a light pulse delivered during the latter part of the dark phase (7 h after lights-off; 55.6 +/- 7.5% of vehicle controls, P < 0.004). Quipazine proto-oncogene c-Fos Mesocricetus auratus
2 injection of the serotonergic, quipazine, caused a marked decrease in the number of SCN cells expressing Fos protein-like immunoreactivity (Fos-LI) induced by a light pulse delivered during the latter part of the dark phase (7 h after lights-off; 55.6 +/- 7.5% of vehicle controls, P < 0.004). Quipazine proto-oncogene c-Fos Mesocricetus auratus
3 In a likewise manner, intra-SCN microinjection of quipazine inhibited light-induced Fos-LI in the ventrolateral SCN, indicating that the suppressive action of quipazine is centered in the SCN. Quipazine proto-oncogene c-Fos Mesocricetus auratus