Title : Adrenocorticotropin-resistant mutants of the Y1 adrenal cell line fail to express the adrenocorticotropin receptor.

Pub. Date : 1995 Apr

PMID : 7896893






1 Functional Relationships(s)
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1 Whereas parental Y1 cells express ACTH receptor transcripts at low levels and are stimulated by ACTH or 8-bromo-cAMP to increase the accumulation of ACTH receptor transcripts approximately twofold, the Y6 and OS3 mutants do not express receptor transcripts either in the presence or absence of 8-bromo-cAMP. 8-Bromo Cyclic Adenosine Monophosphate melanocortin 2 receptor Mus musculus