Title : CO binding kinetics of human cytochrome P450 3A4. Specific interaction of substrates with kinetically distinguishable conformers.

Pub. Date : 1995 Mar 10

PMID : 7890608






1 Functional Relationships(s)
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1 The rate of CO binding to the total mixture of P450 3A4 conformers was increased in the presence of nifedipine and erythromycin, decreased by quinidine, testosterone, and warfarin, and unaffected by cimetidine and 17 alpha-ethynylestradiol. Erythromycin cytochrome P450 family 2 subfamily B member 6 Homo sapiens