Pub. Date : 1994 Dec
PMID : 7889274
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The antithrombotic action of argatroban, a synthetic thrombin inhibitor, was studied in three models of thrombosis in the rat, and in the tail transection bleeding time test. | argatroban | coagulation factor II | Rattus norvegicus |
2 | Hoever, the antithrombotic effects of argatroban were accompanied by only moderate changes in the coagulation parameters (thrombin time and activated partial thromboplastin time, APTT), whereas, even at a subthreshold dose of heparin (12.5 pg kg-1 min-1), both the thrombin time and the APTT were greater than 150 s.5. | argatroban | coagulation factor II | Rattus norvegicus |
3 | Hoever, the antithrombotic effects of argatroban were accompanied by only moderate changes in the coagulation parameters (thrombin time and activated partial thromboplastin time, APTT), whereas, even at a subthreshold dose of heparin (12.5 pg kg-1 min-1), both the thrombin time and the APTT were greater than 150 s.5. | argatroban | coagulation factor II | Rattus norvegicus |