Title : 1-Chloro-2,4-dinitrobenzene is an irreversible inhibitor of human thioredoxin reductase. Loss of thioredoxin disulfide reductase activity is accompanied by a large increase in NADPH oxidase activity.

Pub. Date : 1995 Feb 24

PMID : 7876079






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Human thioredoxin reductase is a dimeric enzyme that catalyzes reduction of the disulfide in oxidized thioredoxin by a mechanism involving transfer of electrons from NADPH via FAD to a redox-active disulfide. Flavin-Adenine Dinucleotide thioredoxin Homo sapiens
2 Human thioredoxin reductase is a dimeric enzyme that catalyzes reduction of the disulfide in oxidized thioredoxin by a mechanism involving transfer of electrons from NADPH via FAD to a redox-active disulfide. Flavin-Adenine Dinucleotide thioredoxin Homo sapiens