Pub. Date : 1994 Oct
PMID : 7865683
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Fibrinogen present in EDTA--anticoagulated plasma stimulates the tissue-type plasminogen activator-catalysed conversion of plasminogen to plasmin. | Edetic Acid | fibrinogen beta chain | Homo sapiens |
| 2 | It was previously shown that treatment of purified fibrinogen by EDTA, which removes the three tightly bound Ca2+ ions, results in exposure of tissue-type plasminogen activator-catalytic sites similar to those unveiled by thrombin. | Edetic Acid | fibrinogen beta chain | Homo sapiens |
| 3 | The most probable explanation is that tissue-type plasminogen activator-stimulating sites are exposed in fibrinogen by EDTA. | Edetic Acid | fibrinogen beta chain | Homo sapiens |