Title : Changes in oncogene mRNA expression during human keratinocyte differentiation.

Pub. Date : 1994

PMID : 7864662






1 Functional Relationships(s)
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1 Treatment with 10 nM TPA, which also induces keratinocyte differentiation, reduced c-myc RNA levels to 70% of control levels during the first 4 h, but thereafter c-myc levels remained approximately constant for a further 20 h. TGF beta (2 ng/ml), which inhibits keratinocyte growth without inducing differentiation, did not alter c-myc RNA levels over a 4-day period. Tetradecanoylphorbol Acetate transforming growth factor beta 1 Homo sapiens