Title : Adaptive resetting of the volume control of vasopressin secretion during sustained hypovolemia.

Pub. Date : 1995 Feb

PMID : 7864228






2 Functional Relationships(s)
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1 We found that an injection of furosemide (10 mg/kg) produced a transient marked increase in urine output, a moderate 7-10% reduction in blood volume, and a three- to fourfold rise in plasma vasopressin from 1.6 +/- 0.2 to 5.6 +/- 1.0 pmol/l. Furosemide arginine vasopressin Rattus norvegicus
2 However, the lines describing the relationship of log plasma vasopressin to plasma volume and plasma sodium in the rats treated with furosemide for 32 h lay to the left of the same relationships in the rats treated for 8 h or the sham-treated controls. Furosemide arginine vasopressin Rattus norvegicus