Pub. Date : 1995 Feb
PMID : 7864155
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Over a broad range of pHi values, total net acid extrusion was approximately four times higher in bilateral presence of CO2/HCO3- than in its absence. | Bicarbonates | glucose-6-phosphate isomerase | Oryctolagus cuniculus |
| 2 | Initial rate of luminal Na(+)-dependent net acid extrusion in presence of CO2/HCO3- was approximately 229 microM/s (pHi 6.92), approximately 1.8 times higher than the flux of approximately 127 microM/s (P < 0.005) obtained in absence of CO2/HCO3- (pHi 6.66). | Bicarbonates | glucose-6-phosphate isomerase | Oryctolagus cuniculus |
| 3 | CO2/HCO3- alkali-shifted the flux vs. pHi relationship by 0.3-0.4 pH units. | Bicarbonates | glucose-6-phosphate isomerase | Oryctolagus cuniculus |
| 4 | Also, Na(+)-independent net acid extrusion rate was approximately two to three times higher in presence than in absence of CO2/HCO3- at comparable pHi. | Bicarbonates | glucose-6-phosphate isomerase | Oryctolagus cuniculus |
| 5 | Stimulation of luminal Na+/H+ exchange and Na(+)-independent acid extrusion appears to be the major, if not the entire, explanation for the higher steady-state pHi caused by bilateral addition of CO2/HCO3-. | Bicarbonates | glucose-6-phosphate isomerase | Oryctolagus cuniculus |