Title : Downregulation of E. coli-induced TNF-alpha expression in perfused liver by hypoxia-reoxygenation.

Pub. Date : 1995 Feb

PMID : 7864128






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1 We tested the hypothesis that reducing the hepatic O2 supply by 30 min of constant-flow hypoxia (PO2, approximately 45 Torr) following gram-negative bacteremia downregulates tumor necrosis factor-alpha (TNF-alpha) in buffer-perfused rat lives (total n = 44). PO-2 tumor necrosis factor Rattus norvegicus
2 We tested the hypothesis that reducing the hepatic O2 supply by 30 min of constant-flow hypoxia (PO2, approximately 45 Torr) following gram-negative bacteremia downregulates tumor necrosis factor-alpha (TNF-alpha) in buffer-perfused rat lives (total n = 44). PO-2 tumor necrosis factor Rattus norvegicus