Title : Major histocompatibility complex class II and III in Addison's disease. MHC alleles do not predict autoantibody specificity and 21-hydroxylase gene polymorphism has no independent role in disease susceptibility.

Pub. Date : 1994 Oct

PMID : 7860358






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The genes encoding the 21OH enzyme are located in the class III segment of the MHC complex. 21oh major histocompatibility complex, class I, C Homo sapiens
2 Also, we tested whether presence of autoantibodies against 21OH is associated with specific alleles in MHC. 21oh major histocompatibility complex, class I, C Homo sapiens
3 The presence of autoantibodies against 21OH was not found to be directly determined by the MHC alleles; rather it was associated with the clinical form of the disease. 21oh major histocompatibility complex, class I, C Homo sapiens