Title : Renal autacoids are involved in the stimulation of renin gene expression by low perfusion pressure.

Pub. Date : 1994 Nov

PMID : 7853791






2 Functional Relationships(s)
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1 These findings indicate that both the inhibition of prostaglandin synthesis and of the formation of endothelium-derived relaxing factor (EDRF) attenuate the increase of renin gene expression and of renin secretion in response to acute unilateral renal hypoperfusion and that the effects of both maneuvers are additive. Prostaglandins renin Rattus norvegicus
2 These findings indicate that both the inhibition of prostaglandin synthesis and of the formation of endothelium-derived relaxing factor (EDRF) attenuate the increase of renin gene expression and of renin secretion in response to acute unilateral renal hypoperfusion and that the effects of both maneuvers are additive. Prostaglandins renin Rattus norvegicus