Title : Choline derivatives and sodium fluoride protect acetylcholinesterase against irreversible inhibition and aging by DFP and paraoxon.

Pub. Date : 1994 Oct

PMID : 7853361






2 Functional Relationships(s)
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1 A light addressable potentiometric sensor was used to measure acetylcholinesterase (AChE) activity in order to evaluate the protective effects of quaternary compounds and NaF against enzyme phosphorylation and aging by two organophosphates. Organophosphates acetylcholinesterase (Cartwright blood group) Homo sapiens
2 The use of the immobilized AChE made possible the quick removal of reagents (i.e., organophosphate, 2-pralidoxime, and protectant), thereby permitting accurate determination of AChE activity before and after phosphorylation and aging. Organophosphates acetylcholinesterase (Cartwright blood group) Homo sapiens