Pub. Date : 1995 Feb
PMID : 7853177
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In the present study, two distinct components of the inhibition of the phenobarbital (PB)-inducible P450 2B1 by parathion were characterized. | Phenobarbital | UDP glucuronosyltransferase family 2 member B17 | Rattus norvegicus |
| 2 | In the present study, two distinct components of the inhibition of the phenobarbital (PB)-inducible P450 2B1 by parathion were characterized. | Phenobarbital | UDP glucuronosyltransferase family 2 member B17 | Rattus norvegicus |
| 3 | At low concentration, parathion was a competitive inhibitor of 2B1-mediated androstenedione 16 beta-hydroxylation (Ki = 0.44 +/- 0.07 microM) and of 7-pentylresorufin O-depentylation (Ki = 0.40 +/- 0.03 microM) in microsomes from PB-pretreated rats and was similarly effective against androstenedione 16 alpha- and 16 beta-hydroxylation catalyzed by purified 2B1. | Phenobarbital | UDP glucuronosyltransferase family 2 member B17 | Rattus norvegicus |