Title : Enhanced tumor necrosis factor suppression and cyclic adenosine monophosphate accumulation by combination of phosphodiesterase inhibitors and prostanoids.

Pub. Date : 1995 Jan

PMID : 7843225






1 Functional Relationships(s)
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1 The effective concentration of PDE inhibitors, which raised cAMP levels to 300% of control, (EC300), correlated with the IC50 for TNF-alpha suppression (r = 0.930, p = 0.007, with theophylline excluded from the analysis). Theophylline cathelicidin antimicrobial peptide Homo sapiens