Pub. Date : 1994 Oct
PMID : 7842009
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Holocarboxylase synthetase (HCS) plays an essential role in biotin utilization in eukaryotic cells and its deficiency causes biotin-responsive multiple carboxylase deficiency in humans. | Biotin | holocarboxylase synthetase | Homo sapiens |
| 2 | Holocarboxylase synthetase (HCS) plays an essential role in biotin utilization in eukaryotic cells and its deficiency causes biotin-responsive multiple carboxylase deficiency in humans. | Biotin | holocarboxylase synthetase | Homo sapiens |
| 3 | Human HCS shows homology to BirA, which acts as both a biotin-[acetyl-CoA-carboxylase] ligase and a biotin repressor in E. coli, suggesting a functional relationship between the two proteins. | Biotin | holocarboxylase synthetase | Homo sapiens |